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| |
With CNS involvement (n = 19)
|
Without CNS involvement (n = 91)
|
P value
|
|---|
|
Treatment, n (%)
| | | |
|
GCs
|
19 (100)
|
88 (96.7)
|
1.000
|
|
MP pulse
|
9 (47.4)
|
22 (24.2)
|
0.041*
|
|
CYC
|
18 (94.7)
|
80 (87.9)
|
0.688
|
|
Rituximab
|
0 (0)
|
1 (1.1)
|
1.000
|
|
Plasma exchange
|
1 (5.3)
|
0 (0)
|
0.173
|
|
IVIG
|
3 (15.8)
|
11 (12.1)
|
0.706
|
|
Outcomes, n (%)
| | | |
|
Complete remission
|
17 (89.5)
|
73 (80.2)
|
0.517
|
|
Partial relief
|
0 (0)
|
12 (13.2)
|
0.122
|
|
Death
|
2 (10.5)
|
6 (6.6)
|
0.625
|
- The categorical variables are expressed as frequencies and ratios, and are further compared by Chi-square analysis or Fisher’s exact test
- EGPA, Eosinophilic Granulomatosis with Polyangiitis; CNS, Central Nervous System; GCs, glucocorticoids (including pulse, high, medium, and low doses); MP, methylprednisolone; CYC, cyclophosphamide (including all kinds of doses); IVIG, Intravenous immunoglobulin; *P< 0.05
